%0 Journal Article %T Silica-Supported Copper Oxide Nanoleaf with Antimicrobial Activity Against Escherichia Coli %J Journal of Water and Environmental Nanotechnology %I Iranian Environmental Mutagen Society %Z 2476-7204 %A Ghorbanpour, Mohammad %A Moghimi, Mohsen %A Lotfiman, Samaneh %D 2017 %\ 04/01/2017 %V 2 %N 2 %P 112-117 %! Silica-Supported Copper Oxide Nanoleaf with Antimicrobial Activity Against Escherichia Coli %K Antimicrobial activity %K Copper oxide %K Nanoleaf %K silica %R 10.22090/jwent.2017.02.006 %X In this research, a simple and fast method was employed to synthesize CuO nanoleaves/silica gel nanocomposites (CuO/SGn), which is a cost effective antimicrobial material. CuSO4.5H2O is the only raw material used in CuO/SGn production through the molten salt method. The structure and morphology of the nanocomposites were characterized by DRS, XRD, and SEM. The copper size in CuO/SG was found to be dependent on the immersion time in molten salt. SEM images revealed smaller-sized particle leaves, from a sample obtained after longer immersion time.The antimicrobial activity of CuO/SGn was investigated against Escherichia coli. The produced CuO/SGn showed inhibitory effect against E. coli. However, the growth-inhibitory effect depends on the copper content and size. Lower loading of CuO nanoparticles in 10 min immersion time resulted in less antibacterial activity (73.33%) and sample obtained from longer immersion time demonstrated higher antibacterial activity (up to 99.96%). The maximum amount of released Cu ions from nanocomposites produced in 90 min was 12.2 ppm after 6 h.  Furthermore, the minimum release of Cu ions was observed by 3 h for 40 min nnanocomposite. %U https://www.jwent.net/article_25071_1f34faba17b6959a5b067210e9782e98.pdf